For the Blue Loop, park at the entrance on Good Hill Road (Route 317) 2 miles east of the Roxbury Green. For most direct access to the Red Loop, use the Old Tophet Road entrance. This can be reached by continuing on Good Hill Road another mile past the first entrance, turning left onto Welton Road and then left onto Tophet Road for 0.5 miles to the parking lot.
Thomas Robert Lilly donated 128 acres to the Roxbury Land Trust in 1975. In 1980, Dione Todd Lilly Bowers gifted 4 acres to the preserve and Thomas R. Bowers and Stewart M. Bowers donated 8 more acres in 1981.